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Real-Time Adherence Monitoring for HIV Antiretroviral Therapy
Current adherence assessments typically detect missed doses long after they occur. Real-time, wireless monitoring strategies for antiretroviral therapy may provide novel opportunities to proactively prevent virologic rebound and treatment failure. Wisepill, a wireless pill container that transmits a cellular signal when opened, was pilot tested in ten Ugandan individuals for 6 months.
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Ugandan Success Story
In Africa, children die of diseases fully preventable and treatable in the developed countries. They vary from the simplest-to-treat conditions like diarrhea and bacterial pneumonia, to the most severe, like malnutrition, tuberculosis and HIV/AIDS
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Adherence data needs to be collected in real time, before the damage is done
Innovative methods to assess a person’s adherence to treatment are being developed which may enable clinicians to intervene and offer support before virological failure occurs, Jessica Haberer told the Fifth International Conference on HIV Treatment Adherence in Miami this week.
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Wisepill an effective tool for Adherence to HIV treatment
Treatment with anti-HIV drugs can mean that you live a longer and healthier life. Some doctors are now optimistic that, thanks to such treatment, many patients with HIV will live a near-normal lifespan.
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Type 2 diabetes : a study of the effects of Real-Time Medication (Dutch)
A watchful medicine box increases the compliance of patients. Of patients who get SMS reminders if they forget their medication, 16% take more of their medication than patients in the control group.The Wisepill real time dispenser and Web application was used to conduct this important study.
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The Wisepill 'Wisebag': an innovative strategy for enhancing measurement of microbicide gel use in clinical trials
The wisebag, (which records opening events and can provide automated reminders) was developed to provide an indirect, objective measure of adherence.
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Wisepill at the MHealth Summit
In his keynote address, NIH Director, Dr Francis Collins discussed the Wisepill device which is deployed by researchers at Massachusetts General Hospital in Uganda, where they are collecting treatment-adherence information about HIV patients, remotely monitoring for lapses in patients taking their antiretroviral medication.
"What it is is basically a pill holder which has within it the ability to send a signal every time the pill box is opened. That, then, will tip you off if there has been a lapse in opening the box. That undoubtedly means there is a lapse in taking the pill," he said.
"I hope you get the sense of NIH's commitment to this, which is really quite wide and deep."
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Bristol-Myers Squibb supports programme powered by Wisepill
The CML Compliance Alliance programme is a collaboration between Bristol-Myers Squibb and Evalan. Bristol-Myers Squibb is a pharmaceutical company and supplies CML medication. Evalan is an innovation company that focusses on developing new services for the health care sector. Evalan provides technical support for the use of the special electronic medication dispensers and the reminder messages service.
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