Wisepill Related Research Papers

  1. Real-Time Adherence Monitoring for HIV Antiretroviral Therapy, 2010

  2. Improving medication adherence in diabetes type 2 patients through Real Time Medication Monitoring: a Randomised Controlled Trial to evaluate the effect of monitoring patients’ medication use combined with short message service (SMS) reminders, 2011

  3. Optimizing network connectivity for mobile health technologies in sub-Saharan Africa. 2012.
  4. Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China, 2013

  5. Real-time Adherence Monitoring of Antiretroviral Therapy Among HIV-infected Adults and Children in Rural Uganda, 2014

  6. A pilot study of a nurse-delivered cognitive behavioural therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa, 2015

  7. Improving Adherence to Antiretroviral Therapy with Triggered Real Time Text Message Reminders: the China through Technology, 2015

  8. A Randomized Controlled Trial of Real-Time Electronic Adherence Monitoring With Text Message Dosing Reminders in People Starting First-Line Antiretroviral Therapy, 2015

  9. Duration of antiretroviral therapy adherence interruption is associated with risk of virologic rebound as determined by real-time adherence monitoring in rural Uganda. 2015

  10. Can Short-Term Use of Electronic Patient Adherence Monitoring Devices Improve Adherence in Patients Failing Second-Line Antiretroviral Therapy? Evidence from a Pilot Study in Johannesburg, South Africa, 2016

  11. SMS reminders plus real-time adherence monitoring improve adherence to antiretroviral therapy in rural Uganda, 2016 

  12. Tenofovir-based oral preexposure prophylaxis prevents HIV infection among women.
  13. The Daily Relationship Between Aspects of Food Insecurity and Medication Adherence Among People Living with HIV with Recent Experiences of Hunger, 2016.
  14. Feasibility, Acceptability, and Tolerability of Targeted Naltrexone for Nondependent Methamphetamine-Using and Binge-Drinking Men Who Have Sex with Men, 2016.

Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China

Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China

Recently, wireless technology has emerged as a potential tool for monitoring medication adherence in real time. This is noteworthy given the recognized association between late dose-timing and loss of viral suppression. One promising tool, the Wisepill personal medication container (Wisepill Technologies, Cape Town, South Africa), detects the exact date and time whenever the patient opens it to access medication. Read More...

Harvard Research : Real-Time Adherence Monitoring for HIV Antiretroviral Therapy

Real-Time Adherence Monitoring for HIV Antiretroviral Therapy

Current adherence assessments typically detect missed doses long after they occur. Real-time, wireless monitoring strategies for antiretroviral therapy may provide novel opportunities to proactively prevent virologic rebound and treatment failure. Wisepill, a wireless pill container that transmits a cellular signal when opened, was pilot tested in ten Ugandan individuals for 6 months. Read More...

Adherence of pediatric patients to ART in rural Uganda

Qualitative analysis of factors influencing adherence of pediatric patients to ART in rural Uganda

Sub-optimal antiretroviral adherence is a serious problem among people living with HIV (PLWH) that can lead to virologic rebound, resistance to medication regimens, and poor health outcomes. Emerging technologies allow for the detection of potential missed doses in real time as a possible point of intervention. Using these sensory technologies, this test of concept intervention trial was designed to target possible missed doses and initiate just-in-time self-regulation adherence counseling..... Read more

Type 2 diabetes Research published : a study of the effects of Real-Time Medication

Type 2 diabetes Research published : a study of the effects of Real-Time Medication

Improving medication adherence in diabetes type 2 patients through Real Time Medication Monitoring

Of patients who get SMS reminders if they forget their medication, 16% take more of their medication than patients in the control group. The Wisepill real time dispenser and Web application was used to conduct this important study. Read more...