Digital adherence technologies (DATs)—which include feature phone–based and smartphone-based technologies, digital pillboxes and ingestible sensors—have the potential to facilitate more patient-centric approaches for monitoring tuberculosis (TB) medication adherence than existing directly observed therapy (DOT) models. Read more
In a statement released on the 1st of May 2018, Unitaid launched a call for proposals to fund innovative projects against TB and drug-resistance. With advances in TB care threatened by drug resistant TB, Unitaid is striving to improve cure rates for people diagnosed with MDR-TB with wider use of best drugs, diagnostics and medication adherence technologies. Wisepill’s evriMED dispensers have been successfully deployed to 1000’s of TB patients worldwide. evriMED is one of a number of innovative tools that can be used to fight TB and for national scale up in countries most affected. The deadline for proposals is Friday, 29 June 2018, 12 Noon CET. For more information on the Unitaid call for proposals, click here.
The Wisepill device shows promise in providing real- time adherence information in a way that is effective and acceptable to the patient. It has the potential to identify lapses in adherence and possibly improve adherence with real-time intervention before these lapses can lead to a negative impact on treatment success. Self-report and pill count depend on patients continuing to attend clinic visits, do not provide data on potential non-adherence in real-time, may be inferior to Wisepill in capturing non-adherence (self- report), and may not provide the reported confidentiality of the Wisepill device. Thus, the use of electronic monitoring devices appears to be applicable to DR-TB treatment in addition to ART, and may have significant advantages to other commonly utilized adherence monitoring methods.
Abstract : Pilot evaluation of a second-generation electronic pill box for adherence to Bedaquiline and antiretroviral therapy in drug-resistant TB/HIV co-infected patients in KwaZulu-Natal, South Africa.
Wisepill Technologies recently invited James Kruger, Director of the HIV AIDS STI & TB Directorate at the Western Cape Department of Health, to visit the Wisepill office in Somerset West followed by a tour of the manufacturing facility where the Wisepill products are produced. The tour showcased the factory processes and the high standard to which each device is manufactured. Mr. Kruger and his team showed great interest in how Wisepill adherence devices are being used in China, India and parts of Africa to manage TB medication adherence. The evriMED devices offer cost-effective adherence monitoring technologies, that enable more patient-centered adherence monitoring options and inform and enable differentiated care to improve health outcomes and reduce TB morbidity and mortality.
“Wisepill Technologies is excited to provide a truly global data solution to our clients enabled by Aeris and its IoT connectivity services. This partnership with Aeris means that Wisepill can provide an awesome customer experience in every corner of the globe.” Ricci Marshall, Owner and Director, Wisepill Technologies Read more..
Wisepill recently launched an eDOT tool for the management of TB which has been successfully used to assist thousands of TB patients in China and in India so I thought this would be of interest to you.
Wisepill's "eDOT" solution: evriMED
Two years ago, with support from the Bill & Melinda Gates Foundation (BMGF), Wisepill developed an eDOT tool for the remote management of TB. The result was a tailor-made product called evriMED which has been included by TB Reach and the Stop TB partnership as an example of a quality, World health Organisation approved monitoring technology.
TB Reach and The BMGF together with USAID and Global Affairs Canada are supporting the TB REACH Wave 6 initiative to fund innovation and research to (i) improve detection, linkage to treatment and reporting of TB, and to (ii) improve TB treatment adherence and outcomes.
Webinar - Leveraging IoT for Medical Monitoring (Tuesday, February 20, 2018 at 9a.m. PT | 12p.m. E)
I also want to take this opportunity to personally invite you to attend a Webinar on the subject of Real Time Medication Management. Wisepill, is a pioneer in real-time medical monitoring management solutions and will be joining Aeris, a leader in IoT technology, to discuss the technology and the future of Medication Adherence Management.
The DTHF team at the Gugulethu Research Offices (GRO) under the direction of local Principal Investigator, Assoc Professor Catherine Orrell, has been involved with this adherence study for the past three years. The aim is to contribute to the work being undertaken on adherence to antiretroviral therapy (ART) to achieve an AIDS-free generation. This is the most comprehensive study to have been undertaken to understand ART by stage of HIV infection in sub-Saharan Africa. There were eleven sites, seven in Mbarara, Uganda and four within the Klipfontein sub-district of Cape Town. The dissemination of findings to stakeholders took place at UCT on 30th January. Read more ...
Improving medication adherence in diabetes type 2 patients through Real Time Medication Monitoring: a Randomised Controlled Trial to evaluate the effect of monitoring patients’ medication use combined with short message service (SMS) reminders, 2011
- Optimizing network connectivity for mobile health technologies in sub-Saharan Africa. 2012.
Can Short-Term Use of Electronic Patient Adherence Monitoring Devices Improve Adherence in Patients Failing Second-Line Antiretroviral Therapy? Evidence from a Pilot Study in Johannesburg, South Africa, 2016
Recently, wireless technology has emerged as a potential tool for monitoring medication adherence in real time. This is noteworthy given the recognized association between late dose-timing and loss of viral suppression. One promising tool, the Wisepill personal medication container (Wisepill Technologies, Cape Town, South Africa), detects the exact date and time whenever the patient opens it to access medication. Read More...
Current adherence assessments typically detect missed doses long after they occur. Real-time, wireless monitoring strategies for antiretroviral therapy may provide novel opportunities to proactively prevent virologic rebound and treatment failure. Wisepill, a wireless pill container that transmits a cellular signal when opened, was pilot tested in ten Ugandan individuals for 6 months. Read More...
Sub-optimal antiretroviral adherence is a serious problem among people living with HIV (PLWH) that can lead to virologic rebound, resistance to medication regimens, and poor health outcomes. Emerging technologies allow for the detection of potential missed doses in real time as a possible point of intervention. Using these sensory technologies, this test of concept intervention trial was designed to target possible missed doses and initiate just-in-time self-regulation adherence counseling..... Read more
Type 2 diabetes Research published : a study of the effects of Real-Time Medication
Of patients who get SMS reminders if they forget their medication, 16% take more of their medication than patients in the control group. The Wisepill real time dispenser and Web application was used to conduct this important study. Read more...